Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation.

نویسندگان

  • David P Smith
  • Jon Anderson
  • Jeffrey Plante
  • Alison E Ashcroft
  • Sheena E Radford
  • Andrew J Wilson
  • Martin J Parker
چکیده

The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.

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عنوان ژورنال:
  • Chemical communications

دوره 44  شماره 

صفحات  -

تاریخ انتشار 2008